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Antibody formation Greater levels of anti-cagrilintide antibodies were detected with higher doses of cagrilintide in clinical trials

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At the same time, the pleiotropic, neurotrophic and neuroprotective properties of GLP-1RAs are also obvious and, taking into account the ability to enhance the energy metabolism of neurons and optimize synaptic plasticity these beneficial effects position GLP-1RAs as potential agents modifying brain diseases [109, 110]

CLINICAL HIGHLIGHTS & LATEST EVIDENCE: Robust HbA1c reduction up to -1.8% with once-weekly dosing

Allergic and non-allergic rhinitis: Approximately 33% of postmenopausal women report chronic cough lasting longer than eight weeks, and life-long endogenous estrogen exposure has been linked to higher rates of allergic rhinitis later in life